A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy

BACKGROUND:Electrocardiographic measures of left ventricular hypertrophy (LVH) are used as predictors of cardiovascular risk. We combined linkage and association analyses to discover novel rare genetic variants involved in three such measures and two principal components derived from them. METHODS:T...

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Bibliographic Details
Main Authors: Silva, C, Zorkoltseva, I, Niemeijer, M, Van Den Berg, M, Amin, N, Demirkan, A, Van Leeuwen, E, Iglesias, A, Piñeros-Hernández, L, Restrepo, C, Kors, J, Kirichenko, A, Willemsen, R, Oostra, B, Stricker, B, Uitterlinden, A, Axenovich, T, Van Duijn, C, Isaacs, A
Format: Journal article
Language:English
Published: BioMed Central 2018