A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy

BACKGROUND:Electrocardiographic measures of left ventricular hypertrophy (LVH) are used as predictors of cardiovascular risk. We combined linkage and association analyses to discover novel rare genetic variants involved in three such measures and two principal components derived from them. METHODS:T...

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Những tác giả chính: Silva, C, Zorkoltseva, I, Niemeijer, M, Van Den Berg, M, Amin, N, Demirkan, A, Van Leeuwen, E, Iglesias, A, Piñeros-Hernández, L, Restrepo, C, Kors, J, Kirichenko, A, Willemsen, R, Oostra, B, Stricker, B, Uitterlinden, A, Axenovich, T, Van Duijn, C, Isaacs, A
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: BioMed Central 2018