Dynamic populations of dendritic cell-specific ICAM-3 grabbing nonintegrin-positive immature dendritic cells and liver/lymph node-specific ICAM-3 grabbing nonintegrin-positive endothelial cells in the outer zones of the paracortex of human lymph nodes.

In the paracortex of lymph nodes, cellular immune responses are generated against antigens captured in peripheral tissues by dendritic cells (DCs). DC-SIGN (dendritic cell-specific ICAM-3 grabbing nonintegrin), a C-type lectin exclusively expressed by DCs, functions as an antigen receptor as well as...

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Bibliographic Details
Main Authors: Engering, A, van Vliet, S, Hebeda, K, Jackson, D, Prevo, R, Singh, S, Geijtenbeek, T, van Krieken, H, van Kooyk, Y
Format: Journal article
Language:English
Published: 2004