Regulation of matrix synthesis rates by the ionic and osmotic environment of articular chondrocytes.
Chondrocytes in cartilage are embedded in a matrix containing a high concentration of proteoglycans and hence of fixed negative charges. Their extracellular ionic environment is thus different from that of most cells, with extracellular Na+ being 250-350 mM and extracellular osmolality 350-450 mOsm....
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1993
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