Profiling of naïve and primed human pluripotent stem cells reveals state-associated miRNAs

Naïve human pluripotent stem cells (hPSC) resemble the embryonic epiblast at an earlier time-point in development than conventional, ‘primed’ hPSC. We present a comprehensive miRNA profiling of naïve-to-primed transition in hPSC, a process recapitulating aspects of early in vivo embryogenesis. We id...

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Bibliographic Details
Main Authors: Dodsworth, BT, Hatje, K, Rostovskaya, M, Flynn, R, Meyer, CA, Cowley, SA
Format: Journal article
Language:English
Published: Nature Research 2020