Profiling of naïve and primed human pluripotent stem cells reveals state-associated miRNAs
Naïve human pluripotent stem cells (hPSC) resemble the embryonic epiblast at an earlier time-point in development than conventional, ‘primed’ hPSC. We present a comprehensive miRNA profiling of naïve-to-primed transition in hPSC, a process recapitulating aspects of early in vivo embryogenesis. We id...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Nature Research
2020
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