Electrochemical nanoreactor provides a comprehensive view of isocitrate dehydrogenase cancer-drug kinetics

The ability to control enzyme cascades entrapped in a nanoporous electrode material (the “Electrochemical Leaf”, e-Leaf) has been exploited to gain detailed kinetic insight into the mechanism of an anti-cancer drug. Ivosidenib, used to treat acute myeloid leukemia, acts on a common cancer-linked var...

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Bibliographic Details
Main Authors: Herold, RA, Schofield, CJ, Armstrong, FA
Format: Journal article
Language:English
Published: Wiley 2023