Construction, arraying, and high-density screening of large insert libraries of human chromosomes X and 21: their potential use as reference libraries.

We have constructed cosmid libraries from flow-sorted human chromosomes X and 21, each of which contains greater than 30 genome equivalents, and have developed systems allowing permanent storage of primary clones, easy screening of libraries in high-density filter formats, and the simultaneous gener...

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Bibliographic Details
Main Authors: Nizetić, D, Zehetner, G, Monaco, A, Gellen, L, Young, B, Lehrach, H
Format: Journal article
Language:English
Published: 1991