Notochordal intervertebral disc cells: sensitivity to nutrient deprivation.

OBJECTIVE: The nucleus pulposus (NP) of the intervertebral disc develops from the notochord. Humans and other species in which notochordal cells (NCs) disappear to be replaced by chondrocyte-like mature NP cells (MNPCs) frequently develop disc degeneration, unlike other species that retain NCs. The...

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Bibliographic Details
Main Authors: Guehring, T, Wilde, G, Sumner, M, Grünhagen, T, Karney, G, Tirlapur, U, Urban, J
Format: Journal article
Language:English
Published: 2009