Notochordal intervertebral disc cells: sensitivity to nutrient deprivation.
OBJECTIVE: The nucleus pulposus (NP) of the intervertebral disc develops from the notochord. Humans and other species in which notochordal cells (NCs) disappear to be replaced by chondrocyte-like mature NP cells (MNPCs) frequently develop disc degeneration, unlike other species that retain NCs. The...
Main Authors: | Guehring, T, Wilde, G, Sumner, M, Grünhagen, T, Karney, G, Tirlapur, U, Urban, J |
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Format: | Journal article |
Language: | English |
Published: |
2009
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