The role of mammalian NEIL1 protein in the repair of 8-oxo-7,8-dihydroadenine in DNA.
8-oxo-7,8-dihydroadenine (8-oxoAde) is a major product of adenine modification by reactive oxygen species. So far, only one mammalian DNA glycosylase, 8-oxoguanine-DNA-glycosylase 1 (OGG1), has been shown to excise 8-oxoAde, exclusively from pairs with Cyt. We have found that endonuclease VIII-like...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2010
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