Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages.

Apicomplexan protozoan pathogens avoid destruction and establish a replicative niche within host cells by forming a nonfusogenic parasitophorous vacuole (PV). Here we present evidence for lysosome-mediated degradation of Toxoplasma gondii after invasion of macrophages activated in vivo. Pathogen eli...

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Bibliographic Details
Main Authors: Ling, Y, Shaw, M, Ayala, C, Coppens, I, Taylor, G, Ferguson, D, Yap, G
Format: Journal article
Language:English
Published: 2006