A cell-cycle-dependent DNA polymerase activity that replicates intact DNA in chromatin.

An insoluble DNA polymerase activity that replicates the intact chromatin template at 85% of the rate found in vivo has been partially characterized. HeLa cells, encapsulated in agarose microbeads, are lysed using an isotonic salt concentration: the resulting encapsulated nuclei contain polymerase a...

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Hlavní autoři: Jackson, D, Cook, P
Médium: Journal article
Jazyk:English
Vydáno: 1986