A cell-cycle-dependent DNA polymerase activity that replicates intact DNA in chromatin.
An insoluble DNA polymerase activity that replicates the intact chromatin template at 85% of the rate found in vivo has been partially characterized. HeLa cells, encapsulated in agarose microbeads, are lysed using an isotonic salt concentration: the resulting encapsulated nuclei contain polymerase a...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1986
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