Molecular analysis of HLA class II associations with hepatitis B virus clearance and vaccine nonresponsiveness.

Clearance of acute hepatitis B virus (HBV) infection is associated with a vigorous CD4+ T-cell response focusing on the core protein. HLA class II glycoproteins present viral peptides to CD4+ T cells and influence the immune responses. HLA-DRB1*1301/2 have been associated with viral clearance, and H...

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Bibliographic Details
Main Authors: Godkin, A, Davenport, M, Hill, A
Format: Journal article
Language:English
Published: 2005