Targeting of liposomes via PSGL1 for enhanced tumor accumulation
Purpose: To improve the delivery of liposomes to tumors using P-selectin glycoprotein ligand 1 (PSGL1) mediated binding to selectin molecules, which are upregulated on tumorassociated endothelium. Methods: PSGL1 was orientated and presented on the surface of liposomes to achieve optimal selectin bin...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2013
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