Targeting of liposomes via PSGL1 for enhanced tumor accumulation
Purpose: To improve the delivery of liposomes to tumors using P-selectin glycoprotein ligand 1 (PSGL1) mediated binding to selectin molecules, which are upregulated on tumorassociated endothelium. Methods: PSGL1 was orientated and presented on the surface of liposomes to achieve optimal selectin bin...
| Auteurs principaux: | , , |
|---|---|
| Format: | Journal article |
| Langue: | English |
| Publié: |
2013
|