On the proportion of cancer stem cells in a tumour

It is now generally accepted that cancers contain a sub-population, the cancer stem cells (CSCs), which initiate and drive a tumour’s growth. At least until recently it has been widely assumed that only a small proportion of the cells in a tumour are CSCs. Here we use a mathematical model, supported...

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Bibliographic Details
Main Authors: Johnston, M, Maini, P, Chapman, S, Edwards, C, Bodmer, W
Format: Journal article
Published: Elsevier 2010