Recombinant modified vaccinia virus Ankara efficiently restimulates human cytotoxic T lymphocytes in vitro.

The immunogenicity of recombinant modified vaccinia Ankara, a highly attenuated vaccinia virus, expressing influenza nucleoprotein (MVA-NP) and HIV-1 gag (MVA-gag) was investigated. Restimulation of peripheral blood lymphocytes of healthy subjects with MVA-NP led to expansion of CTL with specificity...

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Bibliographic Details
Main Authors: Dorrell, L, O'Callaghan, C, Britton, W, Hambleton, S, McMichael, A, Smith, G, Rowland-Jones, S, Blanchard, T
Format: Journal article
Language:English
Published: 2000