Recombinant modified vaccinia virus Ankara efficiently restimulates human cytotoxic T lymphocytes in vitro.
The immunogenicity of recombinant modified vaccinia Ankara, a highly attenuated vaccinia virus, expressing influenza nucleoprotein (MVA-NP) and HIV-1 gag (MVA-gag) was investigated. Restimulation of peripheral blood lymphocytes of healthy subjects with MVA-NP led to expansion of CTL with specificity...
Main Authors: | Dorrell, L, O'Callaghan, C, Britton, W, Hambleton, S, McMichael, A, Smith, G, Rowland-Jones, S, Blanchard, T |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2000
|
Similar Items
-
Optimization of a peptide-based protocol employing IL-7 for in vitro restimulation of human cytotoxic T lymphocyte precursors.
by: Lalvani, A, et al.
Published: (1997) -
Immunisation with recombinant modified vaccinia virus Ankara expressing HIV-1 gag in HIV-1-infected subjects stimulates broad functional CD4+ T cell responses.
by: Ondondo, B, et al.
Published: (2006) -
Effective induction of simian immunodeficiency virus-specific cytotoxic T lymphocytes in macaques by using a multiepitope gene and DNA prime-modified vaccinia virus Ankara boost vaccination regimen.
by: Hanke, T, et al.
Published: (1999) -
Improved Host Range Selection for Recombinant Modified Vaccinia Virus Ankara
by: Caroline Staib, et al.
Published: (2003-04-01) -
Immunodominance of poxviral-specific CTL in a human trial of recombinant-modified vaccinia Ankara.
by: Smith, C, et al.
Published: (2005)