Behavioral effects of manganese injected in the rat substantia nigra are potentiated by dicumarol, a DT-diaphorase inhibitor.

Behavioral effects of manganese injected in the rat substantia nigra are potentiated by dicumarol, a DT-diaphorase inhibitor.

The purpose of this study was to evaluate the contribution of DT-diaphorase inhibition to in vivo neurodegenerative effects of dopamine (DA) oxidation to the corresponding o-quinones. The neurotoxicity to nigrostriatal DA neurons was induced by injection of manganese pyrophosphate (Mn(3+)) complex a...

Bibliografiset tiedot
Päätekijät:	Díaz-Véliz, G, Mora, S, Gómez, P, Dossi, M, Montiel, J, Arriagada, C, Aboitiz, F, Segura-Aguilar, J
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	2004

Samankaltaisia teoksia

Behavioral effects of aminochrome and dopachrome injected in the rat substantia nigra.
Tekijä: Díaz-Véliz, G, et al.
Julkaistu: (2002)

Neuroprotection against Aminochrome Neurotoxicity: Glutathione Transferase M2-2 and DT-Diaphorase
Tekijä: Juan Segura-Aguilar, et al.
Julkaistu: (2022-01-01)

Stereotaxic Injection of LPS into Mouse Substantia Nigra
Tekijä: Huiming Gao
Julkaistu: (2012-04-01)

Behavioural response to bilateral injections of substance P into the substantia nigra of the rat.
Tekijä: Kelley, A, et al.
Julkaistu: (1978)

Proteome analysis of human substantia nigra in Parkinson's disease
Tekijä: Werner Cornelius J, et al.
Julkaistu: (2008-02-01)

Screening for inhibitor of episomal DNA identified dicumarol as a hepatitis B virus inhibitor.
Tekijä: Fumihiko Takeuchi, et al.
Julkaistu: (2019-01-01)

Enhanced training protects memory against amnesia produced by concurrent inactivation of amygdala and striatum, amygdala and substantia nigra, or striatum and substantia nigra
Tekijä: Rigoberto eSalado-Castillo, et al.
Julkaistu: (2011-12-01)

Spontaneous and amphetamine-induced behavior after bilateral injection of ethanolamine-O-sulfate into the substantia nigra.
Tekijä: Koob, G, et al.
Julkaistu: (1978)

Hybrids of 1,4-Quinone with Quinoline Derivatives: Synthesis, Biological Activity, and Molecular Docking with DT-Diaphorase (NQO1)
Tekijä: Monika Kadela-Tomanek, et al.
Julkaistu: (2022-09-01)

Substantia nigra alterations in mice modeling Parkinson’s disease
Tekijä: I. N. Rozhkova, et al.
Julkaistu: (2024-11-01)

Ninetieth Anniversary of Parkinson’s Disease «Substantia Nigra» Theory
Tekijä: O.N. Voskresenskaya, et al.
Julkaistu: (2009-06-01)

Bidirectional modulation of substantia nigra activity by motivational state.
Tekijä: Mark A Rossi, et al.
Julkaistu: (2013-01-01)

Operant self-stimulation of dopamine neurons in the substantia nigra.
Tekijä: Mark A Rossi, et al.
Julkaistu: (2013-01-01)

Sex-Related Abnormalities in Substantia Nigra Lipids in Parkinson’s Disease
Tekijä: T. N. Seyfried, et al.
Julkaistu: (2018-06-01)

Action of Dicumarol on Glucosamine-1-Phosphate Acetyltransferase of GlmU and Mycobacterium tuberculosis
Tekijä: Xiuyan Han, et al.
Julkaistu: (2019-08-01)

Acute Neuroinflammatory Response in the Substantia Nigra Pars Compacta of Rats after a Local Injection of Lipopolysaccharide
Tekijä: Yazmin M. Flores-Martinez, et al.
Julkaistu: (2018-01-01)

ISOLATION AND CHARACTERIZATION OF SINGLE NEURONS FROM GUINEA-PIG SUBSTANTIA-NIGRA
Tekijä: Hainsworth, A, et al.
Julkaistu: (1990)

Imaging of Substantia Nigra in Parkinson’s Disease: A Narrative Review
Tekijä: Paola Feraco, et al.
Julkaistu: (2021-06-01)

Classification of Parkinson’s Disease in Patch-Based MRI of Substantia Nigra
Tekijä: Sayyed Shahid Hussain, et al.
Julkaistu: (2023-08-01)

Ferroptosis-related factors in the substantia nigra are associated with Parkinson’s disease
Tekijä: Lei Liu, et al.
Julkaistu: (2023-09-01)

Anatomical and functional organization of the human substantia nigra and its connections
Tekijä: Yu Zhang, et al.
Julkaistu: (2017-08-01)

The effect of titanium dioxide nanoparticles on mice midbrain substantia nigra
Tekijä: Zahra Heidari, et al.
Julkaistu: (2019-07-01)

Complement activation in the Parkinson's disease substantia nigra: an immunocytochemical study
Tekijä: Conant Stephanie B, et al.
Julkaistu: (2006-10-01)

Genetic and constitutional factors are major contributors to substantia nigra hyperechogenicity
Tekijä: Juan F. Vázquez-Costa, et al.
Julkaistu: (2017-08-01)

Age-mediated transcriptomic changes in adult mouse substantia nigra.
Tekijä: Lin Gao, et al.
Julkaistu: (2013-01-01)

Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease
Tekijä: Christian Dölle, et al.
Julkaistu: (2016-11-01)

Inhibitors of type IV phosphodiesterases reduce the toxicity of MPTP in substantia nigra neurons in vivo.
Tekijä: Hulley, P, et al.
Julkaistu: (1995)

Dicumarol inhibits PDK1 and targets multiple malignant behaviors of ovarian cancer cells.
Tekijä: Wenjia Zhang, et al.
Julkaistu: (2017-01-01)

Diagnostic utility of 7T neuromelanin imaging of the substantia nigra in Parkinson’s disease
Tekijä: Dhairya A. Lakhani, et al.
Julkaistu: (2024-01-01)

Moderate Changes in CO2 Modulate the Firing of Neurons in the VTA and Substantia Nigra
Tekijä: Emily Hill, et al.
Julkaistu: (2020-07-01)

Explorative Combined Lipid and Transcriptomic Profiling of Substantia Nigra and Putamen in Parkinson’s Disease
Tekijä: Helena Xicoy, et al.
Julkaistu: (2020-08-01)

Eyes as Gateways for Environmental Light to the Substantia Nigra: Relevance in Parkinson’s Disease
Tekijä: Stefania Romeo, et al.
Julkaistu: (2014-01-01)

Local iron deficiency in the substantia nigra directly contributes to hyperlocomotion phenotypes
Tekijä: Zhuo Wang, et al.
Julkaistu: (2022-06-01)

Changes in cytoplasmic and extracellular neuromelanin in human substantia nigra with normal aging
Tekijä: Dmitrii E. Korzhevskii, et al.
Julkaistu: (2021-09-01)

Blood-Derived α-Synuclein Aggregated in the Substantia Nigra of Parabiotic Mice
Tekijä: Xizhen Ma, et al.
Julkaistu: (2021-08-01)

Measuring the iron content of dopaminergic neurons in substantia nigra with MRI relaxometry
Tekijä: Malte Brammerloh, et al.
Julkaistu: (2021-10-01)

Verbascoside promotes the regeneration of tyrosine hydroxylase-immunoreactive neurons in the substantia nigra
Tekijä: Jian-qing Liang, et al.
Julkaistu: (2016-01-01)

Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition
Tekijä: Pearce Ronald KB, et al.
Julkaistu: (2005-06-01)

The role of the substantia nigra pars compacta in regulating sleep patterns in rats.
Tekijä: Marcelo M S Lima, et al.
Julkaistu: (2007-06-01)

Intranigral Transplantation of Fetal Substantia Nigra Allograft in the Hemiparkinsonian Rhesus Monkey
Tekijä: Philip A. Starr M.D.,Ph.D., et al.
Julkaistu: (1999-01-01)