Differential regulation of extracellular tissue inhibitor of metalloproteinases-3 levels by cell membrane-bound and shed low density lipoprotein receptor-related protein 1.

Tissue inhibitor of metalloproteinases-3 (TIMP-3) plays a key role in regulating extracellular matrix turnover by inhibiting matrix metalloproteinases (MMPs), adamalysins (ADAMs), and adamalysins with thrombospondin motifs (ADAMTSs). We demonstrate that levels of this physiologically important inhib...

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Bibliographic Details
Main Authors: Scilabra, S, Troeberg, L, Yamamoto, K, Emonard, H, Thøgersen, I, Enghild, J, Strickland, D, Nagase, H
Format: Journal article
Language:English
Published: 2013