Studies towards squalene synthase inhibitors: total synthesis of 6,7-dideoxysqualestatin h5 via an alkene-protection strategy

<p>The zaragozic acids/squalestatins are a family of bicyclic tricarboxylic acids, isolated from a series of different fungi. Members of this class of highly oxygenated natural products show potent inhibitory activity against squalene synthase at the last stage of cholesterol biosynthesis,...

詳細記述

書誌詳細
第一著者: Almohseni, H
その他の著者: Hodgson, D
フォーマット: 学位論文
出版事項: 2019