BLOCKING THE INHIBITORY CD94/NKG2A NK CELL RECEPTOR WITH A NOVEL ANTI-NKG2A MAB ENHANCES THE SUSCEPTIBILITY OF RHEUMATOID ARTHRITIS FIBROBLAST-LIKE SYNOVIOCYTES (FLS) TO NK CELL-MEDIATED CYTOTOXICITY

Míreanna comhchosúla

• HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells.
  de réir: King, A, et al.
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• Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.
  de réir: Nielsen, N, et al.
  Foilsithe / Cruthaithe: (2014)
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• Inhibitory NKG2A+ and absent activating NKG2C+ NK cell responses are associated with the development of EBV+ lymphomas
  de réir: Hannes Vietzen, et al.
  Foilsithe / Cruthaithe: (2023-06-01)