Intracellular antibodies and challenges facing their use as therapeutic agents.
A key feature of antibodies is their ability to bind antigens with high specificity and affinity. This has led to the concept of intracellular antibodies (intrabodies), designed to mimic antibody-antigen binding, but inside cells. Antibody fragments comprising the antigen-binding variable domains ar...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2003
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