Intracellular antibodies and challenges facing their use as therapeutic agents.

A key feature of antibodies is their ability to bind antigens with high specificity and affinity. This has led to the concept of intracellular antibodies (intrabodies), designed to mimic antibody-antigen binding, but inside cells. Antibody fragments comprising the antigen-binding variable domains ar...

Полное описание

Библиографические подробности
Главные авторы: Lobato, M, Rabbitts, T
Формат: Journal article
Язык:English
Опубликовано: 2003