Loop mobility in a four-helix-bundle protein: 15N NMR relaxation measurements on human interleukin-4.
15N NOE, T1, and T2 measurements have been carried out on uniformly 15N-labeled human interleukin-4. Analysis of the results in terms of order parameters (S2) shows that although the helical core of this four-helix-bundle protein exists as a well-defined structure with limited conformational flexibi...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1992
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