A statistical method for predicting classical HLA alleles from SNP data.

A statistical method for predicting classical HLA alleles from SNP data.

Genetic variation at classical HLA alleles is a crucial determinant of transplant success and susceptibility to a large number of infectious and autoimmune diseases. However, large-scale studies involving classical type I and type II HLA alleles might be limited by the cost of allele-typing technolo...

Полное описание

Библиографические подробности
Главные авторы:	Leslie, S, Donnelly, P, McVean, G
Формат:	Journal article
Язык:	English
Опубликовано:	2008

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