Structural characterization of the full-length Hantaan virus polymerase

Hantaviridae are a family of segmented negative-sense RNA viruses that contain important human and animal pathogens. Hantaviridae contain a viral RNA-dependent RNA polymerase that replicates and transcribes the viral genome. Here we establish the expression and purification of the polymerase from th...

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Bibliographic Details
Main Authors: Keown, JR, Carrique, L, Nilsson-Payant, BE, Fodor, E, Grimes, JM
Format: Journal article
Language:English
Published: Public Library of Science 2024