Polymer supported oxazolidin-2-ones derived from L-serine - a cautionary tale

The capacity of N-Boc-4-hydroxymethyl-oxazolidin-2-ones to undergo rapid O-O and N-O acyl transfer makes these serine derived chiral auxiliaries unsuitable for attachment to polymers. (C) 2000 Elsevier Science Ltd.

Bibliografiska uppgifter
Huvudupphovsmän: Bew, S, Bull, S, Davies, S
Materialtyp: Journal article
Språk:English
Publicerad: 2000
Beskrivning
Sammanfattning:The capacity of N-Boc-4-hydroxymethyl-oxazolidin-2-ones to undergo rapid O-O and N-O acyl transfer makes these serine derived chiral auxiliaries unsuitable for attachment to polymers. (C) 2000 Elsevier Science Ltd.