The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent.

An RNA-dependent RNA polymerase (RdRp) is the central catalytic subunit of the RNA-synthesizing machinery of all positive-strand RNA viruses. Usually, RdRp domains are readily identifiable by comparative sequence analysis, but biochemical confirmation and characterization can be hampered by intrinsi...

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Detalles Bibliográficos
Autores principales: te Velthuis, A, Arnold, J, Cameron, C, van den Worm, S, Snijder, E
Formato: Journal article
Lenguaje:English
Publicado: 2010