Essential role for the transcription factor Bhlhe41 in regulating the development, self-renewal and BCR repertoire of B-1a cells

Innate-like B-1a cells provide a first line of defense against pathogens, yet little is known about their transcriptional control. Here we identified an essential role for the transcription factor Bhlhe41, with a lesser contribution by Bhlhe40, in controlling B-1a cell differentiation. Bhlhe41-/-Bhl...

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Bibliographic Details
Main Authors: Kreslavsky, T, Vilagos, B, Tagoh, H, Poliakova, D, Schwickert, T, Wöhner, M, Jaritz, M, Weiss, S, Taneja, R, Rossner, M, Busslinger, M
Format: Journal article
Language:English
Published: Springer Nature 2017