Hyperpolarized ketone body metabolism in the rat heart

The aim of this work was to investigate the use of 13C‐labelled acetoacetate and β‐hydroxybutyrate as novel hyperpolarized substrates in the study of cardiac metabolism. [1‐13C]Acetoacetate was synthesized by catalysed hydrolysis, and both it and [1‐13C]β‐hydroxybutyrate were hyperpolarized by disso...

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Bibliographic Details
Main Authors: Miller, J, Ball, D, Lau, A, Tyler, D
Format: Journal article
Published: Wiley 2018