Single-cell assessment of transcriptome alterations induced by Scriptaid in early differentiated human haematopoietic progenitors during ex vivo expansion
<p>Priming haematopoietic stem/progenitor cells (HSPCs) <em>in vitro</em> with specific chromatin modifying agents and cytokines under serum-free-conditions significantly enhances engraftable HSC numbers. We extend these studies by culturing human CD133+ HSPCs on nanofibre scaffold...
Main Authors: | , , , , , , , , , , |
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Format: | Journal article |
Published: |
Nature Research
2019
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