Single-cell assessment of transcriptome alterations induced by Scriptaid in early differentiated human haematopoietic progenitors during ex vivo expansion

<p>Priming haematopoietic stem/progenitor cells (HSPCs) <em>in vitro</em> with specific chromatin modifying agents and cytokines under serum-free-conditions significantly enhances engraftable HSC numbers. We extend these studies by culturing human CD133+ HSPCs on nanofibre scaffold...

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Bibliographic Details
Main Authors: Hua, P, Kronsteiner, B, Van Der Gard, M, Ashley, N, Hernandez, D, Tarunina, M, Hook, L, Choo, Y, Roberts, I, Mead, A, Watt, S
Format: Journal article
Published: Nature Research 2019