The class I human leukocyte antigen in immune control and intra-host evolution of HIV-1

<p>The CD8+ T (CTL) cell response is an important component of the immune response to HIV-1 infection. Presentation of peptides by the human leukocyte antigen (HLA) class I is key in directing that response. HLA-B*27:05 and HLA-B*57:01 have been consistently associated with immune control of H...

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Bibliographic Details
Main Author: Brener, J
Other Authors: Goulder, P
Format: Thesis
Published: 2015