T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses.

T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses.

Identification of protective T cell responses against SARS-CoV-2 requires distinguishing people infected with SARS-CoV-2 from those with cross-reactive immunity to other coronaviruses. Here we show a range of T cell assays that differentially capture immune function to characterise SARS-CoV-2 respon...

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Bibliographic Details
Main Authors: Ogbe, A, Kronsteiner, B, Skelly, DT, Pace, M, Brown, A, Adland, E, Adair, K, Akhter, HD, Ali, M, Ali, S-E, Angyal, A, Ansari, MA, Arancibia-Cárcamo, CV, Brown, H, Chinnakannan, S, Conlon, C, de Lara, C, de Silva, T, Dold, C, Dong, T, Donnison, T, Eyre, D, Flaxman, A, Fletcher, H, Gardner, J, Grist, JT, Hackstein, C-P, Jaruthamsophon, K, Jeffery, K, Lambe, T, Lee, L, Li, W, Lim, N, Matthews, PC, Mentzer, AJ, Moore, SC, Naisbitt, DJ, Ogese, M, Ogg, G, Openshaw, P, Pirmohamed, M, Pollard, AJ, Ramamurthy, N, Rongkard, P, Rowland-Jones, S, Sampson, O, Screaton, G, Sette, A, Stafford, L, Thompson, C, Klenerman, P, Frater, J, Dunachie, S
Format: Journal article
Language:English
Published: Springer Nature 2021

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