A fluorescent probe identifies active site ligands of inositol pentakisphosphate 2-kinase

Inositol pentakisphosphate 2-kinase catalyzes the phosphorylation of the axial 2-OH of myo-inositol 1,3,4,5,6-pentakisphosphate for de novo synthesis of myo-inositol hexakisphosphate. Disruption of inositol pentakisphosphate 2-kinase profoundly influences cellular processes, from nuclear mRNA export...

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Bibliographic Details
Main Authors: Whitfield, H, Gilmartin, M, Baker, K, Riley, A, Godage, H, Potter, B, Hemmings, A, Brearley, C
Format: Journal article
Published: American Chemical Society 2018