Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel

Centrioles are eukaryotic organelles that template the formation of cilia and flagella, as well as organize the microtubule network and the mitotic spindle in animal cells. Centrioles have proximal-distal polarity and a 9-fold radial symmetry imparted by a likewise symmetrical central scaffold, the...

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Bibliographic Details
Main Authors: Kantsadi, AL, Hatzopoulos, GN, Gönczy, P, Vakonakis, I
Format: Journal article
Language:English
Published: Cell Press 2022