The CD46-Jagged1 interaction is critical for human TH1 immunity.

CD46 is a complement regulator with important roles related to the immune response. CD46 functions as a pathogen receptor and is a potent costimulator for the induction of interferon-γ (IFN-γ)-secreting effector T helper type 1 (T(H)1) cells and their subsequent switch into interleukin 10 (IL-10)-pr...

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Bibliographic Details
Main Authors:	Le Friec, G, Sheppard, D, Whiteman, P, Karsten, C, Shamoun, SA, Laing, A, Bugeon, L, Dallman, M, Melchionna, T, Chillakuri, C, Smith, R, Drouet, C, Couzi, L, Fremeaux-Bacchi, V, Köhl, J, Waddington, SN, McDonnell, J, Baker, A, Handford, P, Lea, S, Kemper, C
Format:	Journal article
Language:	English
Published:	2012

The CD46-Jagged1 interaction is critical for human TH1 immunity.

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