Disease model distortion in association studies
Most findings from genome-wide association studies (GWAS) are consistent with a simple disease model at a singel nucleotide polymorphism, in which each additional copy of the risk allele increases risk by the same multiplicative factor, in contrast to dominance or interaction effects. As others have...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
Wiley
2011
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Subjects: |