Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis

Chronic inflammatory diseases like rheumatoid arthritis are characterized by a deficit in fully functional regulatory T cells. DNA-methylation inhibitors have previously been shown to promote regulatory T cell responses and, in the present study, we evaluated their potential to ameliorate chronic an...

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Bibliographic Details
Main Authors: Huang, Y-S, Tseng, W-Y, Clanchy, FIL, Topping, ML, Ogbechi, J, McNamee, K, Perocheau, D, Chiang, N-Y, Ericsson, P, Sundstedt, A, Xue, Z-T, Salford, LG, Sjögren, H-O, Stone, TW, Lin, H-H, Luo, S-F, Williams, RO
Format: Journal article
Language:English
Published: National Academy of Sciences 2021