Inflammatory Ly-6C(hi) monocytes play an important role in the development of severe transplant arteriosclerosis in hyperlipidemic recipients.

OBJECTIVE: Transplant arteriosclerosis (TA) restricts long-term survival of heart transplant recipients. Although the role of monocyte/macrophages is well established in native atherosclerosis, it has been studied to a much lesser extent in TA. Plasma cholesterol is the most important non-immunologi...

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Bibliographic Details
Main Authors: Schiopu, A, Nadig, SN, Cotoi, O, Hester, J, van Rooijen, N, Wood, K
Format: Journal article
Language:English
Published: 2012