Improving the affinity and activity of CYP101D2 for hydrophobic substrates.

CYP101D2 is a cytochrome P450 monooxygenase from Novosphingobium aromaticivorans which is closely related to CYP101A1 (P450cam) from Pseudomonas putida. Both enzymes selectively hydroxylate camphor to 5-exo-hydroxycamphor, and the residues that line the active sites of both enzymes are similar inclu...

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Bibliographic Details
Main Authors: Bell, S, Yang, W, Dale, A, Zhou, W, Wong, L
Format: Journal article
Language:English
Published: 2013