Transcriptional termination in mammals: Stopping the RNA polymerase II juggernaut.

Terminating transcription is a highly intricate process for mammalian protein-coding genes. First, the chromatin template slows down transcription at the gene end. Then, the transcript is cleaved at the poly(A) signal to release the messenger RNA.The remaining transcript is selectively unraveled and...

Full description

Bibliographic Details
Main Author: Proudfoot, N
Format: Journal article
Language:English
Published: American Association for the Advancement of Science 2016