Identification of loci associated with schizophrenia by genome-wide association and follow-up.

We carried out a genome-wide association study of schizophrenia (479 cases, 2,937 controls) and tested loci with P < 10(-5) in up to 16,726 additional subjects. Of 12 loci followed up, 3 had strong independent support (P < 5 x 10(-4)), and the overall pattern of replication was unlikel...

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Main Authors: O'Donovan, M, Craddock, N, Norton, N, Williams, H, Peirce, T, Moskvina, V, Nikolov, I, Hamshere, M, Carroll, L, Georgieva, L, Dwyer, S, Holmans, P, Marchini, J, Spencer, C, Howie, B, Leung, H, Hartmann, A, Möller, H, Morris, D, Shi, Y, Feng, G, Hoffmann, P, Propping, P, Vasilescu, C, Maier, W
Format: Journal article
Language:English
Published: 2008