An investigation of the role of ASPP2 in HIF signaling and cancer

<p>The ability to sense and respond to hypoxia is essential for the survival of living organisms and is frequently co-opted by tumor cells to adapt to hypoxic microenvironment. As the pivotal transcription factor for hypoxic responses, the hypoxia inducible factors (HIFs) transactivate a wide...

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Bibliographic Details
Main Author: Chan, HF
Other Authors: Lu, X
Format: Thesis
Language:English
Published: 2020
Subjects: