An investigation of the role of ASPP2 in HIF signaling and cancer

An investigation of the role of ASPP2 in HIF signaling and cancer

<p>The ability to sense and respond to hypoxia is essential for the survival of living organisms and is frequently co-opted by tumor cells to adapt to hypoxic microenvironment. As the pivotal transcription factor for hypoxic responses, the hypoxia inducible factors (HIFs) transactivate a wide...

书目详细资料
主要作者:	Chan, HF
其他作者:	Lu, X
格式:	Thesis
语言:	English
出版:	2020
主题:	Cancer cell signaling Hypoxia

相似书籍

Independence of HIF1a and androgen signaling pathways in prostate cancer
由: Maxine G. B. Tran, et al.
出版: (2020-05-01)

The role of ASPP2 in intestinal homeostasis and tumourigenesis
由: Qin, X
出版: (2017)

An oxygen-insensitive Hif-3α isoform inhibits Wnt signaling by destabilizing the nuclear β-catenin complex
由: Peng Zhang, et al.
出版: (2016-01-01)

Calcitriol Suppresses HIF-1 and HIF-2 Transcriptional Activity by Reducing HIF-1/2α Protein Levels via a VDR-Independent Mechanism
由: Ioanna-Maria Gkotinakou, et al.
出版: (2020-11-01)

Notch signaling, hypoxia, and cancer
由: Mingzhou Guo, et al.
出版: (2023-01-01)

Investigating the role of iASPP and ASPP2 in human carcinoma
由: Salter, V
出版: (2014)

Hypoxia-inducible factor HIF-1α modulates drugs resistance in colon cancer cells
由: Martha Leonor Pinzón-Daza, et al.
出版: (2018-10-01)

ERK signaling controls productive HIF‐1 binding to chromatin and cancer cell adaptation to hypoxia through HIF‐1α interaction with NPM1
由: Kreon Koukoulas, et al.
出版: (2021-12-01)

Hypoxia-induced chemoresistance in cancer cells: The role of not only HIF-1
由: Helena Doktorova, et al.
出版: (2015-06-01)

Investigation of the role of ASPP2 in tumourigenesis
由: Tordella, L
出版: (2012)

SOX2 promotes hypoxia-induced breast cancer cell migration by inducing NEDD9 expression and subsequent activation of Rac1/HIF-1α signaling
由: Yueyuan Wang, et al.
出版: (2019-08-01)

HIF1α Regulates IL17 Signaling Pathway Influencing Sensitivity of Taxane-Based Chemotherapy for Breast Cancer
由: Huijuan Dai, et al.
出版: (2021-09-01)

EZH2, HIF-1, and Their Inhibitors: An Overview on Pediatric Cancers
由: Marco Papale, et al.
出版: (2018-11-01)

Investigating the role of iASPP in cutaneous disorders
由: Dedeić, Z
出版: (2014)

Impact of HIF-1α, LOX and ITGA5 Synergistic Interaction in the Tumor Microenvironment on Colorectal Cancer Prognosis
由: Hayriye Tatlı Doğan, et al.
出版: (2025-01-01)

Investigation of ASPPs as regulators of pancreatic inflammation and tumorigenesis
由: Miller, P
出版: (2018)

Prolonged Hypoxic Exposure Impairs Endothelial Functions: Possible Mechanism of HIF-1α Signaling
由: Junyoung Hong, et al.
出版: (2024-05-01)

Hypoxia/HIF Modulates Immune Responses
由: Yuling Chen, et al.
出版: (2021-03-01)

HIF and MYC signaling in adrenal neoplasms of the neural crest: implications for pediatrics
由: Nicole Bechmann, et al.
出版: (2023-06-01)

Transcriptional Response to Hypoxia: The Role of HIF-1-Associated Co-Regulators
由: Angelos Yfantis, et al.
出版: (2023-03-01)

Exploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish models
由: Philip M. Elks, et al.
出版: (2015-11-01)

The Hypoxia-Inducible Factor (HIF) pathway in adipocytes: The role of HIF-2 in adipose inflammation and hypertrophic cardiomyopathy
由: Zhong eYun, et al.
出版: (2015-03-01)

Exploring the Role of Hypoxia and HIF-1α in the Intersection of Type 2 Diabetes Mellitus and Endometrial Cancer
由: Alagappan V. S. Geetha, et al.
出版: (2025-02-01)

The Contribution of Plant Dioxygenases to Hypoxia Signaling
由: Sergio Iacopino, et al.
出版: (2020-07-01)

Long-Noncoding RNA (lncRNA) in the Regulation of Hypoxia-Inducible Factor (HIF) in Cancer
由: Dominik A. Barth, et al.
出版: (2020-07-01)

HIF-1-Independent Mechanisms Regulating Metabolic Adaptation in Hypoxic Cancer Cells
由: Shen-Han Lee, et al.
出版: (2021-09-01)

Immunometabolism and Sepsis: A Role for HIF?
由: Susan F. Fitzpatrick
出版: (2019-09-01)

A Comprehensive Review on Environmental and Microenvironmental Oxygen Sensing Pathways Mediated by Hypoxia-Inducible Factors (HIFs)
由: Fatemeh Choopani, et al.
出版: (2019-06-01)

HER2 regulates HIF-2α and drives an increased hypoxic response in breast cancer
由: Edward J. Jarman, et al.
出版: (2019-01-01)

HIF-1 signaling: A key orchestrator of cancer radioresistance
由: Ruixue Huang, et al.
出版: (2020-03-01)

Naringenin-loaded nanoparticles modulate HIF-driven oxygen-sensing pathways in lung adenocarcinoma cells
由: Eman M. Ragab, et al.
出版: (2025-02-01)

Hypoxia represses early responses of prostate and renal cancer cells to YM155 independent of HIF-1α and HIF-2α
由: David Danielpour, et al.
出版: (2022-01-01)

HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells
由: Eloy Moreno Roig, et al.
出版: (2019-01-01)

A specific tRNA half, 5’tiRNA-His-GTG, responds to hypoxia via the HIF1α/ANG axis and promotes colorectal cancer progression by regulating LATS2
由: En-Wei Tao, et al.
出版: (2021-02-01)

LAT1 expression in colorectal cancer cells is unresponsive to HIF-1/2α accumulation under experimental hypoxia
由: Ryuichi Ohgaki, et al.
出版: (2024-08-01)

NanoFIRE: A NanoLuciferase and Fluorescent Integrated Reporter Element for Robust and Sensitive Investigation of HIF and Other Signalling Pathways
由: Alison E. Roennfeldt, et al.
出版: (2023-10-01)

The marine-derived HIF-1α inhibitor, Yardenone 2, reduces prostate cancer cell proliferation by targeting HIF-1 target genes
由: Siyong Peng, et al.
出版: (2024-07-01)

HIF1 Contributes to Hypoxia-Induced Pancreatic Cancer Cells Invasion via Promoting QSOX1 Expression
由: Chen-Ye Shi, et al.
出版: (2013-08-01)

AKT, a Key Transmitter of HIF-1α and AR Signaling Pathways, Has a Critical Role in the Apigetrin-Mediated Anti-Cancer Effects in Prostate Cancer Cells
由: You-Kyung Lee, et al.
出版: (2022-06-01)

HIF2α-dependent Dock4/Rac1-signaling regulates formation of adherens junctions and cell polarity in normoxia
由: I. Raykhel, et al.
出版: (2024-05-01)