Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses.

Most non-nucleoside reverse transcriptase (RT) inhibitors are specific for HIV-1 RT and demonstrate minimal inhibition of HIV-2 RT. However, we report that members of the phenylethylthiazolylthiourea (PETT) series of non-nucleoside reverse transcriptase inhibitors showing high potency against HIV-1...

Full description

Bibliographic Details
Main Authors: Ren, J, Diprose, J, Warren, J, Esnouf, R, Bird, L, Ikemizu, S, Slater, M, Milton, J, Balzarini, J, Stuart, D, Stammers, D
Format: Journal article
Language:English
Published: 2000