Optimisation strategies for directed evolution without sequencing

Directed evolution can enable engineering of biological systems with minimal knowledge of their underlying sequence-to-function relationships. A typical directed evolution process consists of iterative rounds of mutagenesis and selection that are designed to steer changes in a biological system (e.g...

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Bibliographic Details
Main Authors: James, J, Towers, S, Foerster, J, Steel, H
Format: Journal article
Language:English
Published: Public Library of Science 2024