Regulation of calcium in pancreatic α- and β-cells in health and disease.
The glucoregulatory hormones insulin and glucagon are released from the β- and α-cells of the pancreatic islets. In both cell types, secretion is secondary to firing of action potentials, Ca(2+)-influx via voltage-gated Ca(2+)-channels, elevation of [Ca(2+)](i) and initiation of Ca(2+)-dependent exo...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
2012
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