Regulation of calcium in pancreatic α- and β-cells in health and disease.

The glucoregulatory hormones insulin and glucagon are released from the β- and α-cells of the pancreatic islets. In both cell types, secretion is secondary to firing of action potentials, Ca(2+)-influx via voltage-gated Ca(2+)-channels, elevation of [Ca(2+)](i) and initiation of Ca(2+)-dependent exo...

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Bibliographic Details
Main Authors: Rorsman, P, Braun, M, Zhang, Q
Format: Journal article
Language:English
Published: 2012