Lapatinib potentiates cytotoxicity of YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter

Adverse side effects of cancer agents are of great concern in the context of childhood tumors where they can reduce the quality of life in young patients and cause life-long adverse effects. Synergistic drug combinations can lessen potential toxic side effects through lower dosing and simultaneously...

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Bibliographic Details
Main Authors: Radic-Sarikas, B, Halasz, M, Huber, K, Winter, G, Tsafou, K, Papamarkou, T, Brunak, S, Kolch, W, Superti-Furga, G
Format: Journal article
Language:English
Published: Springer Nature 2017